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Inhibition of Heat Shock Induction of Heat Shock Protein 70 and Enhancement of Heat Shock Protein 27 Phosphorylation by Quercetin Derivatives

Inhibitors of heat-induced heat shock protein 70 (HSP70) expression have the potential to enhance the therapeutic effectiveness of heat induced radiosensitization of tumors. Among known small molecule inhibitors, quercetin has the advantage of being easily modified for structure-activity studies. He...

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Autori principali: Wang, Rongsheng E., Kao, Jeffrey L.-F., Hilliard, Carolyn A., Pandita, Raj K., Roti, Joseph L. Roti, Hunt, Clayton R., Taylor, John-Stephen
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763579/
https://ncbi.nlm.nih.gov/pubmed/19296652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm801445c
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