Role of Mitofusin 2 in the Renal Stress Response

The role of mitofusin 2 (MFN2), a key regulator of mitochondrial morphology and function in the renal stress response is unknown. To assess its role, the MFN2 floxed gene was conditionally deleted in the kidney of mice (MFN2 cKO) by Pax2 promoter driven Cre expression (Pax2Cre). MFN2 cKO caused seve...

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Detalhes bibliográficos
Main Authors: Gall, Jonathan M., Wang, Zhiyong, Liesa, Marc, Molina, Anthony, Havasi, Andrea, Schwartz, John H., Shirihai, Orian, Borkan, Steven C., Bonegio, Ramon G. B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266928/
https://ncbi.nlm.nih.gov/pubmed/22292091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031074
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