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Nucleophosmin, a Critical Bax Cofactor in Ischemia-Induced Cell Death
We hypothesized that nucleophosmin (NPM), a nucleolar phosphoprotein, is critical for Bax-mediated cell death. To test this hypothesis, Bax activation was induced by metabolic stress. During stress, nucleolar NPM translocated into the cytosol, NPM-Bax complexes formed, and both NPM and Bax accumulat...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3647959/ https://ncbi.nlm.nih.gov/pubmed/23459946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00015-13 |
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