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Adenylate Kinase 4 Promotes Inflammatory Gene Expression via Hif1α and AMPK in Macrophages

Macrophages comprise the front line of defense against various pathogens. Classically activated macrophages (M1), induced by IFN-γ and LPS, highly express inflammatory cytokines and contribute to inflammatory processes. By contrast, alternatively activated macrophages (M2) are induced by IL-4 and IL...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Chin, Wei-Yao, He, Chi-Ying, Chow, Tsun Wai, Yu, Qi-You, Lai, Liang-Chuan, Miaw, Shi-Chuen
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8005550/
https://ncbi.nlm.nih.gov/pubmed/33790902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.630318
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