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Activation of PI3K/AKT/mTOR Pathway Causes Drug Resistance in Breast Cancer

Although chemotherapy, targeted therapy and endocrine therapy decrease rate of disease recurrence in most breast cancer patients, many patients exhibit acquired resistance. Hyperactivation of the PI3K/AKT/mTOR pathway is associated with drug resistance and cancer progression. Currently, a number of...

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Bibliografiska uppgifter
I publikationen:Front Pharmacol
Huvudupphovsmän: Dong, Chao, Wu, Jiao, Chen, Yin, Nie, Jianyun, Chen, Ceshi
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8005514/
https://ncbi.nlm.nih.gov/pubmed/33790792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.628690
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