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Activation of PI3K/AKT/mTOR Pathway Causes Drug Resistance in Breast Cancer

Although chemotherapy, targeted therapy and endocrine therapy decrease rate of disease recurrence in most breast cancer patients, many patients exhibit acquired resistance. Hyperactivation of the PI3K/AKT/mTOR pathway is associated with drug resistance and cancer progression. Currently, a number of...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Dong, Chao, Wu, Jiao, Chen, Yin, Nie, Jianyun, Chen, Ceshi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8005514/
https://ncbi.nlm.nih.gov/pubmed/33790792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.628690
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