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Activation of PI3K/AKT/mTOR Pathway Causes Drug Resistance in Breast Cancer
Although chemotherapy, targeted therapy and endocrine therapy decrease rate of disease recurrence in most breast cancer patients, many patients exhibit acquired resistance. Hyperactivation of the PI3K/AKT/mTOR pathway is associated with drug resistance and cancer progression. Currently, a number of...
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| 出版年: | Front Pharmacol |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Frontiers Media S.A.
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8005514/ https://ncbi.nlm.nih.gov/pubmed/33790792 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.628690 |
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