Unexpected Pleiotropic Effects of SGLT2 Inhibitors: Pearls and Pitfalls of This Novel Antidiabetic Class

Sodium-glucose co-transporter 2 (SGLT2) inhibitors facilitate urine glucose excretion by reducing glucose reabsorption, leading to ameliorate glycemic control. While the main characteristics of type 2 diabetes mellitus are insufficient insulin secretion and insulin resistance, SGLT2 inhibitors have...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Autores principales: Kaneto, Hideaki, Obata, Atsushi, Kimura, Tomohiko, Shimoda, Masashi, Kinoshita, Tomoe, Matsuoka, Taka-aki, Kaku, Kohei
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8002535/
https://ncbi.nlm.nih.gov/pubmed/33802741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22063062
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