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Pleiotropic Roles of PDX-1 in the Pancreas

It is well known that pancreatic and duodenal homeobox factor-1 (PDX-1) plays a pleiotropic role in the pancreas. In the developing pancreas, PDX-1 is involved in both pancreas formation and β-cell differentiation. In mature β-cells, PDX-1 transactivates insulin and other β-cell-related genes such a...

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Detalhes bibliográficos
Main Authors: Kaneto, Hideaki, Miyatsuka, Takeshi, Kawamori, Dan, Matsuoka, Taka-aki
Formato: Artigo
Idioma:Inglês
Publicado em: SBDR - Society for Biomedical Diabetes Research 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2270408/
https://ncbi.nlm.nih.gov/pubmed/18338074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1900/RDS.2007.4.209
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