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Pleiotropic Roles of PDX-1 in the Pancreas
It is well known that pancreatic and duodenal homeobox factor-1 (PDX-1) plays a pleiotropic role in the pancreas. In the developing pancreas, PDX-1 is involved in both pancreas formation and β-cell differentiation. In mature β-cells, PDX-1 transactivates insulin and other β-cell-related genes such a...
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| Glavni autori: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
SBDR - Society for Biomedical Diabetes Research
2007
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2270408/ https://ncbi.nlm.nih.gov/pubmed/18338074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1900/RDS.2007.4.209 |
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