Involvement of Oxidative Stress and the JNK Pathway in Glucose Toxicity

The hallmark of type 2 diabetes is pancreatic β-cell dysfunction and insulin resistance. Normal β-cells can compensate for insulin resistance by increasing insulin secretion, but insufficient compensation leads to the onset of glucose intolerance. Once hyperglycemia becomes apparent, β-cell function...

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Detalles Bibliográficos
Autores principales: Kaneto, Hideaki, Nakatani, Yoshihisa, Kawamori, Dan, Miyatsuka, Takeshi, Matsuoka, Taka-aki
Formato: Artigo
Lenguaje:Inglês
Publicado: SBDR - Society for Biomedical Diabetes Research 2004
Materias:
Review
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783693/
https://ncbi.nlm.nih.gov/pubmed/17491701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1900/RDS.2004.1.165
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