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Involvement of Oxidative Stress and the JNK Pathway in Glucose Toxicity
The hallmark of type 2 diabetes is pancreatic β-cell dysfunction and insulin resistance. Normal β-cells can compensate for insulin resistance by increasing insulin secretion, but insufficient compensation leads to the onset of glucose intolerance. Once hyperglycemia becomes apparent, β-cell function...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
SBDR - Society for Biomedical Diabetes Research
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1783693/ https://ncbi.nlm.nih.gov/pubmed/17491701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1900/RDS.2004.1.165 |
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