Notable Underlying Mechanism for Pancreatic β-Cell Dysfunction and Atherosclerosis: Pleiotropic Roles of Incretin and Insulin Signaling

Under healthy conditions, pancreatic β-cells produce and secrete the insulin hormone in response to blood glucose levels. Under diabetic conditions, however, β-cells are compelled to continuously secrete larger amounts of insulin to reduce blood glucose levels, and thereby, the β-cell function is de...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Kaneto, Hideaki, Obata, Atsushi, Kimura, Tomohiko, Shimoda, Masashi, Sanada, Junpei, Fushimi, Yoshiro, Katakami, Naoto, Matsuoka, Takaaki, Kaku, Kohei
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7763860/
https://ncbi.nlm.nih.gov/pubmed/33322512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21249444
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