Multifaceted Mechanisms of Action of Metformin Which Have Been Unraveled One after Another in the Long History

While there are various kinds of drugs for type 2 diabetes mellitus at present, in this review article, we focus on metformin which is an insulin sensitizer and is often used as a first-choice drug worldwide. Metformin mainly activates adenosine monophosphate-activated protein kinase (AMPK) in the l...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Kaneto, Hideaki, Kimura, Tomohiko, Obata, Atsushi, Shimoda, Masashi, Kaku, Kohei
Format: Artigo
Language:Inglês
Published: MDPI 2021
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7962041/
https://ncbi.nlm.nih.gov/pubmed/33807522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052596
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