Mechanisms of Transthyretin Inhibition of IAPP Amyloid Formation

Amyloid-formation by the islet amyloid polypeptide (IAPP), produced by the β-cells in the human pancreas, has been associated with the development of type II diabetes mellitus (T2DM). The human plasma-protein transthyretin (TTR), a well-known amyloid-inhibiting protein, is interestingly also express...

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Pubblicato in:Biomolecules
Autori principali: Wasana Jayaweera, Sanduni, Surano, Solmaz, Pettersson, Nina, Oskarsson, Elvira, Lettius, Lovisa, Gharibyan, Anna L., Anan, Intissar, Olofsson, Anders
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8001701/
https://ncbi.nlm.nih.gov/pubmed/33802170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11030411
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