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Inhibition of Glycosaminoglycan Mediated Amyloid Formation by Islet Amyloid Polypeptide and pro-IAPP Processing Intermediates
Islet amyloid polypeptide, (IAPP, Amylin), is responsible for islet amyloid formation in type 2 diabetes and IAPP induced toxicity is believed to contribute to the loss of β-cell mass associated with the late stages of type 2 diabetes. Islet amyloid formation may also play a role in graft failure af...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3199970/ https://ncbi.nlm.nih.gov/pubmed/21195086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.12.028 |
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