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Combined Inactivation of Pocket Proteins and APC/C(Cdh1) by Cdk4/6 Controls Recovery from DNA Damage in G1 Phase
Most Cyclin-dependent kinases (Cdks) are redundant for normal cell division. Here we tested whether these redundancies are maintained during cell cycle recovery after a DNA damage-induced arrest in G1. Using non-transformed RPE-1 cells, we find that while Cdk4 and Cdk6 act redundantly during normal...
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| Publicado no: | Cells |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7999910/ https://ncbi.nlm.nih.gov/pubmed/33806417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10030550 |
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