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Cell cycle-dependent nuclear export of Cdh1p may contribute to the inactivation of APC/C(Cdh1)

Cdh1p is a substrate-specific subunit of the anaphase-promoting complex (APC/C), which functions as an E3 ubiquitin ligase to degrade the mitotic cyclin Clb2p and other substrates during the G(1) phase of the cell cycle. Cdh1p is phosphorylated and thereby inactivated at the G(1)/S transition predom...

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Hlavní autoři: Jaquenoud, Malika, van Drogen, Frank, Peter, Matthias
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC136938/
https://ncbi.nlm.nih.gov/pubmed/12456658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf634
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