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The function of APC/C(Cdh1 )in cell cycle and beyond
The anaphase promoting complex/cyclosome (APC/C) is a multi-subunit E3 ubiquitin ligase playing essential functions in mitosis. It is conserved from yeast to human and relies on two adaptor proteins, Cdc20 and Cdh1, to bring in substrates. Both APC(Cdc20 )and APC(Cdh1 )are implicated in the control...
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Format: | Artigo |
Jezik: | Inglês |
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BioMed Central
2009
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Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2635356/ https://ncbi.nlm.nih.gov/pubmed/19152694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1747-1028-4-2 |
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