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Irreversible APC(Cdh1) Inactivation Underlies the Point of No Return for Cell-Cycle Entry
Proliferating cells must cross a point of no return before they replicate their DNA and divide. This commitment decision plays a fundamental role in cancer and degenerative diseases and has been proposed to be mediated by phosphorylation of retinoblastoma (Rb) protein. Here, we show that inactivatio...
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| Publicado no: | Cell |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6649667/ https://ncbi.nlm.nih.gov/pubmed/27368103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.05.077 |
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