Disulfiram Acts as a Potent Radio-Chemo Sensitizer in Head and Neck Squamous Cell Carcinoma Cell Lines and Transplanted Xenografts

The poor prognosis of locally advanced and metastatic head and neck squamous cell carcinoma (HNSCC) is primarily mediated by the functional properties of cancer stem cells (CSCs) and resistance to chemoradiotherapy. We investigated whether the aldehyde dehydrogenase (ALDH) inhibitor disulfiram (DSF)...

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Detaylı Bibliyografya
Yayımlandı:Cells
Asıl Yazarlar: Yao, Wenhao, Qian, Xu, Ochsenreither, Sebastian, Soldano, Ferrone, DeLeo, Albert B., Sudhoff, Holger, Oppel, Felix, Kuppig, Andreas, Klinghammer, Konrad, Kaufmann, Andreas M., Albers, Andreas E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7999545/
https://ncbi.nlm.nih.gov/pubmed/33671083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10030517
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