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Disulfiram Acts as a Potent Radio-Chemo Sensitizer in Head and Neck Squamous Cell Carcinoma Cell Lines and Transplanted Xenografts

The poor prognosis of locally advanced and metastatic head and neck squamous cell carcinoma (HNSCC) is primarily mediated by the functional properties of cancer stem cells (CSCs) and resistance to chemoradiotherapy. We investigated whether the aldehyde dehydrogenase (ALDH) inhibitor disulfiram (DSF)...

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發表在:Cells
Main Authors: Yao, Wenhao, Qian, Xu, Ochsenreither, Sebastian, Soldano, Ferrone, DeLeo, Albert B., Sudhoff, Holger, Oppel, Felix, Kuppig, Andreas, Klinghammer, Konrad, Kaufmann, Andreas M., Albers, Andreas E.
格式: Artigo
語言:Inglês
出版: MDPI 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7999545/
https://ncbi.nlm.nih.gov/pubmed/33671083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10030517
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