Llwytho...

Combination of copanlisib with cetuximab improves tumor response in cetuximab-resistant patient-derived xenografts of head and neck cancer

Despite recent advances, the treatment of head and neck squamous cell carcinoma (HNSCC) remains an area of high unmet medical need. HNSCC is frequently associated with either amplification or mutational changes in the PI3K pathway, making PI3K an attractive target particularly in cetuximab-resistant...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: Klinghammer, Konrad, Politz, Oliver, Eder, Theresa, Otto, Raik, Raguse, Jan-Dirk, Albers, Andreas, Kaufmann, Andreas, Tinhofer, Ingeborg, Hoffmann, Jens, Keller, Ulrich, Keilholz, Ulrich
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7566806/
https://ncbi.nlm.nih.gov/pubmed/33110476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27763
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