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Chemical proteomic identification of functional cysteines with atypical electrophile reactivities
Cysteine-directed covalent ligands have emerged as a versatile category of chemical probes and drugs that leverage thiol nucleophilicity to form permanent adducts with proteins of interest. Understanding the scope of cysteines that can be targeted by covalent ligands, as well as the types of electro...
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| Yayımlandı: | Tetrahedron Lett |
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| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2021
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7996670/ https://ncbi.nlm.nih.gov/pubmed/33776155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2021.152861 |
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