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Chemical proteomic identification of functional cysteines with atypical electrophile reactivities
Cysteine-directed covalent ligands have emerged as a versatile category of chemical probes and drugs that leverage thiol nucleophilicity to form permanent adducts with proteins of interest. Understanding the scope of cysteines that can be targeted by covalent ligands, as well as the types of electro...
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| Wydane w: | Tetrahedron Lett |
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| Główni autorzy: | , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2021
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7996670/ https://ncbi.nlm.nih.gov/pubmed/33776155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2021.152861 |
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