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Chemical proteomic identification of functional cysteines with atypical electrophile reactivities
Cysteine-directed covalent ligands have emerged as a versatile category of chemical probes and drugs that leverage thiol nucleophilicity to form permanent adducts with proteins of interest. Understanding the scope of cysteines that can be targeted by covalent ligands, as well as the types of electro...
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| Publicado no: | Tetrahedron Lett |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7996670/ https://ncbi.nlm.nih.gov/pubmed/33776155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2021.152861 |
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