Aging and pathological aging signatures of the brain: through the focusing lens of SIRT6

Brain-specific SIRT6-KO mice present increased DNA damage, learning impairments, and neurodegenerative phenotypes, placing SIRT6 as a key protein in preventing neurodegeneration. In the aging brain, SIRT6 levels/activity decline, which is accentuated in Alzheimer’s patients. To understand SIRT6 role...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Aging (Albany NY)
Главные авторы: Stein, Daniel, Mizrahi, Amir, Golova, Anastasia, Saretzky, Adam, Venzor, Alfredo Garcia, Slobodnik, Zeev, Kaluski, Shai, Einav, Monica, Khrameeva, Ekaterina, Toiber, Debra
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals 2021
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7993737/
https://ncbi.nlm.nih.gov/pubmed/33690173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202755
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы