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Directed evolution of SIRT6 for improved deacylation and glucose homeostasis maintenance
Mammalian SIRT6 is a well-studied histone deacetylase that was recently shown to exhibit high protein deacylation activity enabling the removal of long chain fatty acyl groups from proteins. SIRT6 was shown to play key roles in cellular homeostasis by regulating a variety of cellular processes inclu...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5824787/ https://ncbi.nlm.nih.gov/pubmed/29476161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21887-9 |
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