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FACS-based isolation of fixed mouse neuronal nuclei for ATAC-seq and Hi-C

The organization of chromatin structure plays a crucial role in gene expression, DNA replication, and repair. Chromatin alterations influence gene expression, and modifications could be associated with genomic instability in the cells during aging or diseases. Here, we provide a modified protocol to...

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Detalhes bibliográficos
Publicado no:STAR Protoc
Main Authors: Eremenko, Ekaterina, Golova, Anastasia, Stein, Daniel, Einav, Monica, Khrameeva, Ekaterina, Toiber, Debra
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8283150/
https://ncbi.nlm.nih.gov/pubmed/34308377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xpro.2021.100643
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