TBMT-01. HYPERPOLARIZED δ-[1-(13)C]GLUCONOLACTONE MONITORS TERT-INDUCED ELEVATION IN PENTOSE PHOSPHATE PATHWAY FLUX IN BRAIN TUMORS IN VIVO

Telomerase reverse transcriptase (TERT) expression is essential for tumor proliferation and is an attractive therapeutic target for gliomas. TERT expression has previously been shown to enhance glucose flux via the pentose phosphate pathway (PPP) in low grade gliomas expressing TERT. Hyperpolarized...

詳細記述

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書誌詳細
出版年:Neurooncol Adv
主要な著者: Batsios, Georgios, Viswanath, Pavithra, Taglang, Celine, Flavell, Robert, Costello, Joseph, Pieper, Russell O, Larson, Peder, Ronen, Sabrina
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2021
主題:
Supplement Abstracts
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7992198/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdab024.083
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