TBMT-01. HYPERPOLARIZED δ-[1-(13)C]GLUCONOLACTONE MONITORS TERT-INDUCED ELEVATION IN PENTOSE PHOSPHATE PATHWAY FLUX IN BRAIN TUMORS IN VIVO

Telomerase reverse transcriptase (TERT) expression is essential for tumor proliferation and is an attractive therapeutic target for gliomas. TERT expression has previously been shown to enhance glucose flux via the pentose phosphate pathway (PPP) in low grade gliomas expressing TERT. Hyperpolarized...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Neurooncol Adv
Asıl Yazarlar: Batsios, Georgios, Viswanath, Pavithra, Taglang, Celine, Flavell, Robert, Costello, Joseph, Pieper, Russell O, Larson, Peder, Ronen, Sabrina
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2021
Konular:
Supplement Abstracts
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7992198/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdab024.083
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