TBMT-01. HYPERPOLARIZED δ-[1-(13)C]GLUCONOLACTONE MONITORS TERT-INDUCED ELEVATION IN PENTOSE PHOSPHATE PATHWAY FLUX IN BRAIN TUMORS IN VIVO

Telomerase reverse transcriptase (TERT) expression is essential for tumor proliferation and is an attractive therapeutic target for gliomas. TERT expression has previously been shown to enhance glucose flux via the pentose phosphate pathway (PPP) in low grade gliomas expressing TERT. Hyperpolarized...

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Vydáno v:Neurooncol Adv
Hlavní autoři: Batsios, Georgios, Viswanath, Pavithra, Taglang, Celine, Flavell, Robert, Costello, Joseph, Pieper, Russell O, Larson, Peder, Ronen, Sabrina
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2021
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Supplement Abstracts
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7992198/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdab024.083
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