CBMT-08. IN VIVO EVALUATION OF PENTOSE PHOSPHATE PATHWAY ACTIVITY IN ORTHOTOPIC GLIOMA USING HYPERPOLARIZED δ-[1-(13)C]GLUCONOLACTONE

The pentose phosphate pathway (PPP) generates NADPH and ribose 5-phosphate, which are involved in the scavenging of reactive oxygen species and the synthesis of nucleotides. As such, the PPP is typically upregulated in cancer cells to address the metabolic needs of rapid cell proliferation. Imaging...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neuro Oncol
Prif Awduron: Batsios, Georgios, Viswanath, Pavithra, Cao, Peng, Taglang, Celine, Subramani, Elavarasan, Flavell, Robert, Larson, Peder, Ronen, Sabrina
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2019
Pynciau:
Cell Biology and Metabolism
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847728/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.130
Tagiau: Ychwanegu Tag
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