CBMT-08. IN VIVO EVALUATION OF PENTOSE PHOSPHATE PATHWAY ACTIVITY IN ORTHOTOPIC GLIOMA USING HYPERPOLARIZED δ-[1-(13)C]GLUCONOLACTONE

The pentose phosphate pathway (PPP) generates NADPH and ribose 5-phosphate, which are involved in the scavenging of reactive oxygen species and the synthesis of nucleotides. As such, the PPP is typically upregulated in cancer cells to address the metabolic needs of rapid cell proliferation. Imaging...

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Bibliografiska uppgifter
I publikationen:Neuro Oncol
Huvudupphovsmän: Batsios, Georgios, Viswanath, Pavithra, Cao, Peng, Taglang, Celine, Subramani, Elavarasan, Flavell, Robert, Larson, Peder, Ronen, Sabrina
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2019
Ämnen:
Cell Biology and Metabolism
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847728/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.130
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