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Hyperpolarized δ-[1-(13)C]gluconolactone as a probe of the pentose phosphate pathway
The pentose phosphate pathway (PPP) is thought to be upregulated in trauma (to produce excess NADPH) and in cancer (to provide ribose for nucleotide biosynthesis) but simple methods for detecting changes in flux through this pathway are not available. Magnetic resonance imaging of hyperpolarized (13...
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| 出版年: | NMR Biomed |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5502806/ https://ncbi.nlm.nih.gov/pubmed/28272754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.3713 |
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