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Hyperpolarized δ-[1-(13)C]gluconolactone as a probe of the pentose phosphate pathway
The pentose phosphate pathway (PPP) is thought to be upregulated in trauma (to produce excess NADPH) and in cancer (to provide ribose for nucleotide biosynthesis) but simple methods for detecting changes in flux through this pathway are not available. Magnetic resonance imaging of hyperpolarized (13...
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| Izdano u: | NMR Biomed |
|---|---|
| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5502806/ https://ncbi.nlm.nih.gov/pubmed/28272754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.3713 |
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