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Hyperpolarized δ-[1-(13)C]gluconolactone as a probe of the pentose phosphate pathway

The pentose phosphate pathway (PPP) is thought to be upregulated in trauma (to produce excess NADPH) and in cancer (to provide ribose for nucleotide biosynthesis) but simple methods for detecting changes in flux through this pathway are not available. Magnetic resonance imaging of hyperpolarized (13...

詳細記述

保存先:
書誌詳細
出版年:NMR Biomed
主要な著者: Moreno, Karlos X., Harrison, Crystal E., Merritt, Matthew E., Kovacs, Zoltan, Malloy, Craig R., Sherry, A. Dean
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502806/
https://ncbi.nlm.nih.gov/pubmed/28272754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.3713
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