Hyperpolarized δ-[1-(13)C]gluconolactone as a probe of the pentose phosphate pathway

The pentose phosphate pathway (PPP) is thought to be upregulated in trauma (to produce excess NADPH) and in cancer (to provide ribose for nucleotide biosynthesis) but simple methods for detecting changes in flux through this pathway are not available. Magnetic resonance imaging of hyperpolarized (13...

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Detaylı Bibliyografya
Yayımlandı:NMR Biomed
Asıl Yazarlar: Moreno, Karlos X., Harrison, Crystal E., Merritt, Matthew E., Kovacs, Zoltan, Malloy, Craig R., Sherry, A. Dean
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502806/
https://ncbi.nlm.nih.gov/pubmed/28272754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.3713
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