CBMT-41. IMAGING A HALLMARK OF CANCER: HYPERPOLARIZED (13)C-MAGNETIC RESONANCE SPECTROSCOPY CAN NON-INVASIVELY MONITOR TERT EXPRESSION IN LOW-GRADE GLIOMAS IN VIVO

Telomerase reverse transcriptase (TERT) expression is a hallmark of cancer, including in primary glioblastomas and low-grade oligodendrogliomas. Since TERT is essential for glioma proliferation and is an attractive therapeutic target, metabolic imaging of TERT status can inform on tumor progression...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: Viswanath, Pavithra, Batsios, Georgios, Marie Gillespie, Anne, Pieper, Russell O, Ronen, Sabrina
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
Soggetti:
Cell Biology and Metabolism
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847492/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.163
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