BIMG-02. IMAGING IMMORTALITY: TERT EXPRESSION ALTERS GLUCOSE METABOLISM IN LOW-GRADE GLIOMAS IN A MANNER THAT CAN BE LEVERAGED FOR NONINVASIVE METABOLIC IMAGING

Telomerase reverse transcriptase (TERT) is essential for tumor immortality and uncontrolled proliferation, including in low-grade oligodendrogliomas (LGOGs). Since it is silenced in somatic cells, TERT is also a therapeutic target. Non-invasive imaging of TERT can differentiate tumor from normal bra...

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Bibliographic Details
Published in:Neurooncol Adv
Main Authors: Viswanath, Pavithra, Batsios, Georgios, Gillespie, Anne Marie, Luchman, Hema Artee, Costello, Joseph, Pieper, Russell, Ronen, Sabrina
Format: Artigo
Language:Inglês
Published: Oxford University Press 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7992259/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdab024.001
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