CBMT-02. UP-REGULATION OF Γ-GLUTAMYL-TRANSFERASE CAN BE USED TO IMAGE GLIOBLASTOMA USING HYPERPOLARIZED Γ-GLUTAMYL-[1-(13)C]GLYCINE MRS

γ-glutamyl-transferase (GGT) is a key enzyme in the γ-glutamyl cycle, which regulates glutathione homeostasis. The enzyme is localized on the outer cell membrane and cleaves glutathione to glutamate and cysteinylglycine. As such, it facilitates uptake of the amino acids essential for intracellular s...

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Detaylı Bibliyografya
Yayımlandı:Neuro Oncol
Asıl Yazarlar: Batsios, Georgios, Najac, Chloe, Cao, Peng, Viswanath, Pavithra, Subramani, Elavarasan, Saito, Yutaro, Marie Gillespie, Anne, Yoshihara, Hikari, Larson, Peder, Sando, Shinsuke, Ronen, Sabrina
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2019
Konular:
Cell Biology and Metabolism
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847274/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.124
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