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Cephalosporin Prodrug Inhibitors Overcome Metallo‐β‐Lactamase Driven Antibiotic Resistance

The increasing prevalence of metallo‐β‐lactamase (MBL)‐expressing bacteria presents a worrying trend in antibiotic resistance. MBLs rely on active site zinc ions for their hydrolytic activity and the pursuit of MBL‐inhibitors has therefore involved the investigation of zinc chelators. To ensure that...

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Bibliografiset tiedot
Julkaisussa:Chemistry
Päätekijät: van Haren, Matthijs J., Tehrani, Kamaleddin H. M. E., Kotsogianni, Ioli, Wade, Nicola, Brüchle, Nora C., Mashayekhi, Vida, Martin, Nathaniel I.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2021
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7986777/
https://ncbi.nlm.nih.gov/pubmed/33237604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.202004694
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