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Thiol-Containing Metallo-β-Lactamase Inhibitors Resensitize Resistant Gram-Negative Bacteria to Meropenem

[Image: see text] The prevalence of infections caused by metallo-β-lactamase (MBL) expressing Gram-negative bacteria has grown at an alarming rate in recent years. Despite the fact that MBLs can deactivate virtually all β-lactam antibiotics, there are as of yet no approved drugs available that inhib...

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Bibliografische gegevens
Gepubliceerd in:ACS Infect Dis
Hoofdauteurs: Tehrani, Kamaleddin Haj Mohammad Ebrahim, Martin, Nathaniel I.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Chemical Society 2017
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5644712/
https://ncbi.nlm.nih.gov/pubmed/28820574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.7b00094
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