Characterization of Plasmodium falciparum Pantothenate Kinase and Identification of Its Inhibitors From Natural Products

Coenzyme A (CoA) is a well-known cofactor that plays an essential role in many metabolic reactions in all organisms. In Plasmodium falciparum, the most deadly among Plasmodium species that cause malaria, CoA and its biosynthetic pathway have been proven to be indispensable. The first and rate-limiti...

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Enregistré dans:
Détails bibliographiques
Publié dans:Front Cell Infect Microbiol
Auteurs principaux: Nurkanto, Arif, Jeelani, Ghulam, Santos, Herbert J., Rahmawati, Yulia, Mori, Mihoko, Nakamura, Yumi, Goto, Kana, Saikawa, Yoko, Annoura, Takeshi, Tozawa, Yuzuru, Sakura, Takaya, Inaoka, Daniel Ken, Shiomi, Kazuro, Nozaki, Tomoyoshi
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2021
Sujets:
Cellular and Infection Microbiology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7985445/
https://ncbi.nlm.nih.gov/pubmed/33768012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2021.639065
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