Discovery of Antiamebic Compounds That Inhibit Cysteine Synthase From the Enteric Parasitic Protist Entamoeba histolytica by Screening of Microbial Secondary Metabolites

Amebiasis is caused by infection with the protozoan parasite Entamoeba histolytica. Although metronidazole has been a drug of choice against amebiasis for decades, it shows side effects and low efficacy against asymptomatic cyst carriers. In addition, metronidazole resistance has been documented for...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Mori, Mihoko, Tsuge, Satoshi, Fukasawa, Wataru, Jeelani, Ghulam, Nakada-Tsukui, Kumiko, Nonaka, Kenichi, Matsumoto, Atsuko, Ōmura, Satoshi, Nozaki, Tomoyoshi, Shiomi, Kazuro
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Cellular and Infection Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290340/
https://ncbi.nlm.nih.gov/pubmed/30568921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2018.00409
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