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Genetic, metabolomic and transcriptomic analyses of the de novo L-cysteine biosynthetic pathway in the enteric protozoan parasite Entamoeba histolytica

The de novo L-cysteine biosynthetic pathway is critical for the growth, antioxidative stress defenses, and pathogenesis of bacterial and protozoan pathogens, such as Salmonella typhimurium and Entamoeba histolytica. This pathway involves two key enzymes, serine acetyltransferase (SAT) and cysteine s...

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Publicat a:Sci Rep
Autors principals: Jeelani, Ghulam, Sato, Dan, Soga, Tomoyoshi, Nozaki, Tomoyoshi
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5688106/
https://ncbi.nlm.nih.gov/pubmed/29142277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15923-3
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