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Genetic, metabolomic and transcriptomic analyses of the de novo L-cysteine biosynthetic pathway in the enteric protozoan parasite Entamoeba histolytica

The de novo L-cysteine biosynthetic pathway is critical for the growth, antioxidative stress defenses, and pathogenesis of bacterial and protozoan pathogens, such as Salmonella typhimurium and Entamoeba histolytica. This pathway involves two key enzymes, serine acetyltransferase (SAT) and cysteine s...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Jeelani, Ghulam, Sato, Dan, Soga, Tomoyoshi, Nozaki, Tomoyoshi
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5688106/
https://ncbi.nlm.nih.gov/pubmed/29142277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15923-3
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