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Genetic, metabolomic and transcriptomic analyses of the de novo L-cysteine biosynthetic pathway in the enteric protozoan parasite Entamoeba histolytica

The de novo L-cysteine biosynthetic pathway is critical for the growth, antioxidative stress defenses, and pathogenesis of bacterial and protozoan pathogens, such as Salmonella typhimurium and Entamoeba histolytica. This pathway involves two key enzymes, serine acetyltransferase (SAT) and cysteine s...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Jeelani, Ghulam, Sato, Dan, Soga, Tomoyoshi, Nozaki, Tomoyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5688106/
https://ncbi.nlm.nih.gov/pubmed/29142277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15923-3
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