Two Atypical l-Cysteine-regulated NADPH-dependent Oxidoreductases Involved in Redox Maintenance, l-Cystine and Iron Reduction, and Metronidazole Activation in the Enteric Protozoan Entamoeba histolytica

We discovered novel catalytic activities of two atypical NADPH-dependent oxidoreductases (EhNO1/2) from the enteric protozoan parasite Entamoeba histolytica. EhNO1/2 were previously annotated as the small subunit of glutamate synthase (glutamine:2-oxoglutarate amidotransferase) based on similarity t...

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Detalhes bibliográficos
Main Authors: Jeelani, Ghulam, Husain, Afzal, Sato, Dan, Ali, Vahab, Suematsu, Makoto, Soga, Tomoyoshi, Nozaki, Tomoyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930688/
https://ncbi.nlm.nih.gov/pubmed/20592025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.106310
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