Characterization of Plasmodium falciparum Pantothenate Kinase and Identification of Its Inhibitors From Natural Products

Coenzyme A (CoA) is a well-known cofactor that plays an essential role in many metabolic reactions in all organisms. In Plasmodium falciparum, the most deadly among Plasmodium species that cause malaria, CoA and its biosynthetic pathway have been proven to be indispensable. The first and rate-limiti...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Nurkanto, Arif, Jeelani, Ghulam, Santos, Herbert J., Rahmawati, Yulia, Mori, Mihoko, Nakamura, Yumi, Goto, Kana, Saikawa, Yoko, Annoura, Takeshi, Tozawa, Yuzuru, Sakura, Takaya, Inaoka, Daniel Ken, Shiomi, Kazuro, Nozaki, Tomoyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Cellular and Infection Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7985445/
https://ncbi.nlm.nih.gov/pubmed/33768012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2021.639065
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