A Detailed Analysis of Parameters Supporting the Engraftment and Growth of Chronic Lymphocytic Leukemia Cells in Immune-Deficient Mice

Patient-derived xenograft models of chronic lymphocytic leukemia (CLL) can be created using highly immunodeficient animals, allowing analysis of primary tumor cells in an in vivo setting. However, unlike many other tumors, CLL B lymphocytes do not reproducibly grow in xenografts without manipulation...

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Detaylı Bibliyografya
Yayımlandı:Front Immunol
Asıl Yazarlar: Patten, Piers E. M., Ferrer, Gerardo, Chen, Shih-Shih, Kolitz, Jonathan E., Rai, Kanti R., Allen, Steven L., Barrientos, Jacqueline C., Ioannou, Nikolaos, Ramsay, Alan G., Chiorazzi, Nicholas
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2021
Konular:
Immunology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7985329/
https://ncbi.nlm.nih.gov/pubmed/33767698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.627020
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