Mechanistic insights into CpG DNA and IL-15 synergy in promoting B-cell chronic lymphocytic leukemia clonal expansion()

Malignant cell growth within patients with B cell chronic lymphocytic leukemia (B-CLL) is largely restricted to lymphoid tissues, particularly lymph nodes. The recent in vitro finding that TLR-9 ligand (ODN) and IL-15 exhibit strong synergy in promoting B-CLL growth may be particularly relevant to g...

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Gepubliceerd in:J Immunol
Hoofdauteurs: Gupta, Rashmi, Yan, Xiao J, Barrientos, Jacqueline, Kolitz, Jonathan E, Allen, Steven L, Rai, Kanti, Chiorazzi, Nicholas, Mongini, Patricia KA
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6103916/
https://ncbi.nlm.nih.gov/pubmed/30068596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800591
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