TLR-9 and IL-15 Synergy Promotes the In Vitro Clonal Expansion of Chronic Lymphocytic Leukemia B Cells

Clinical progression of B cell chronic lymphocytic leukemia (B-CLL) reflects the clone’s Ag receptor (BCR) and involves stroma-dependent B-CLL growth within lymphoid tissue. Uniformly elevated expression of TLR-9, occasional MYD88 mutations, and BCR specificity for DNA or Ags physically linked to DN...

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Detaylı Bibliyografya
Yayımlandı:J Immunol
Asıl Yazarlar: Mongini, Patricia K. A., Gupta, Rashmi, Boyle, Erin, Nieto, Jennifer, Lee, Hyunjoo, Stein, Joanna, Bandovic, Jela, Stankovic, Tatjana, Barrientos, Jacqueline, Kolitz, Jonathan E., Allen, Steven L., Rai, Kanti, Chu, Charles C., Chiorazzi, Nicholas
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: AAI 2015
Konular:
Clinical and Human Immunology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505957/
https://ncbi.nlm.nih.gov/pubmed/26136429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1403189
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