A p53 AXIS REGULATES BCR-TRIGGERED, INNATE IMMUNE SYSTEM-DRIVEN B CELL CLONAL EXPANSION()

Resting mature human B cells undergo a dynamic process of clonal expansion, followed by clonal contraction, during an in vitro response to surrogate C3d-coated antigen and innate immune system cytokines, IL-4 and BAFF. We here explore the mechanism for clonal contraction through following the time-...

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Hauptverfasser: Lee, Hyunjoo, Haque, Shabirul, Nieto, Jennifer, Trott, Joshua, Inman, John K., McCormick, Steven, Chiorazzi, Nicholas, Mongini, Patricia K. A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370112/
https://ncbi.nlm.nih.gov/pubmed/22611237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103037
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