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TRIF Is Required for TLR4 Mediated Adjuvant Effects on T Cell Clonal Expansion

Toll like receptor 4 (TLR4) is an important pattern recognition receptor with the ability to drive potent innate immune responses and also to modulate adaptive immune responses needed for long term protection. Activation of TLR4 by its ligands is mediated by engagement of the adapter proteins MyD88...

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Detalhes bibliográficos
Main Authors: Gandhapudi, Siva K., Chilton, Paula M., Mitchell, Thomas C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574014/
https://ncbi.nlm.nih.gov/pubmed/23457630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056855
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