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WDFY1 mediates TLR3/4 signaling by recruiting TRIF
Toll-like receptors (TLRs) are pattern recognition receptors that sense a variety of pathogens, initiate innate immune responses, and direct adaptive immunity. All TLRs except TLR3 recruit the adaptor MyD88 to ultimately elicit inflammatory gene expression, whereas TLR3 and internalized TLR4 use TIR...
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| Publicado no: | EMBO Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4388611/ https://ncbi.nlm.nih.gov/pubmed/25736436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201439637 |
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