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ZCCHC3 modulates TLR3-mediated signaling by promoting recruitment of TRIF to TLR3
Toll-like receptor 3 (TLR3)-mediated signaling is important for host defense against RNA virus. Upon viral RNA stimulation, toll and interleukin-1 receptor domain-containing adaptor inducing IFN-β (TRIF) is recruited to TLR3 and then undergoes oligomerization, which is required for the recruitment o...
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| Publicado en: | J Mol Cell Biol |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7232131/ https://ncbi.nlm.nih.gov/pubmed/32133501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjaa004 |
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