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Exacerbation of allergen-induced eczema in TLR4 and TRIF deficient mice is mediated by TRIF

Despite its presence on resident skin cells, the role of TLR4 in skin diseases remains poorly understood. This is highly significant since the skin biome is rich with potential TLR4 agonists. We aimed to establish the contribution of TLR4 to atopic dermatitis and determine the mechanism by which TLR...

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Bibliographic Details
Main Authors: Brandt, Eric B., Gibson, Aaron M., Bass, Stacey, Rydyznski, Carolyn, Khurana Hershey, Gurjit K.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3788607/
https://ncbi.nlm.nih.gov/pubmed/23997219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300789
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