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EGFR signaling blunts allergen-induced IL-6 production and Th17 responses in the skin and attenuates development and relapse of atopic dermatitis

Despite the important role for epidermal growth factor (EGF) in epithelial homeostasis and wound healing, it has not been investigated in atopic dermatitis (AD). We used AD animal models to explore the role of EGF in AD. In an acute AD model, skin trans-epidermal water loss (TEWL) was significantly...

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Bibliografische gegevens
Hoofdauteurs: Zhang, Zhonghua, Xiao, Chang, Gibson, Aaron M., Bass, Stacey A., Khurana Hershey, Gurjit K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946981/
https://ncbi.nlm.nih.gov/pubmed/24337738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301062
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