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EGFR signaling blunts allergen-induced IL-6 production and Th17 responses in the skin and attenuates development and relapse of atopic dermatitis

Despite the important role for epidermal growth factor (EGF) in epithelial homeostasis and wound healing, it has not been investigated in atopic dermatitis (AD). We used AD animal models to explore the role of EGF in AD. In an acute AD model, skin trans-epidermal water loss (TEWL) was significantly...

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Autors principals: Zhang, Zhonghua, Xiao, Chang, Gibson, Aaron M., Bass, Stacey A., Khurana Hershey, Gurjit K.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946981/
https://ncbi.nlm.nih.gov/pubmed/24337738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301062
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